ACDC/Adiponectin Polymorphisms Are Associated With Severe Childhood and Adult Obesity

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ACDC/adiponectin polymorphisms are associated with severe childhood and adult obesity.

Common single nucleotide polymorphisms (SNPs) in the ACDC adiponectin encoding gene have been associated with insulin resistance and type 2 diabetes in several populations. Here, we investigate the role of SNPs -11,377C > G, -11,391G > A, +45T > G, and +276G > T in 2,579 French Caucasians (1,229 morbidly obese and 1,350 control subjects). We found an association between severe forms of obesity ...

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ژورنال

عنوان ژورنال: Diabetes

سال: 2006

ISSN: 0012-1797,1939-327X

DOI: 10.2337/diabetes.55.02.06.db05-0971